• USA Home
  • SMB00914 - Isovanillic Acid 3-Sulfate Disodium Salt

EMAIL THIS PAGE TO A FRIEND
SMB00914 Sigma-Aldrich

Isovanillic Acid 3-Sulfate Disodium Salt

≥96% (HPLC)

Synonym: Isovanillic acid 3-sulfate disodium salt

Purchase

Properties

assay   ≥96% (HPLC)
form   powder
color   , White to off-white
solubility   water: 40 mg/mL
storage temp.   2-8°C
SMILES string   COC(C=C1)=C(OS(=O)(O[Na])=O)C=C1C(O[Na])=O

Description

General description

Isovanillic acid 3-O-sulfate (IVAS) is a gut microbial phenolic metabolite primarily derived from consumed cyanidin 3-O-glucoside, a major compound in berry fruits. IVAS is the most effective among the gut microbial phenolic metabolites tested to enhance glucose uptake & metabolism in human skeletal muscle myoblast LHCN-M2. IIVAS is shown to increase glucose transport via GLUT4- and PI3K-dependent mechanisms. IVAS also upregulates GLUT1, GLUT4, PI3K p85a protein level, and Akt phosphorylation, establishing a novel link between gut microbiota, host diet and skeletal muscle energy source utilization.Also another study shows that IVAS restores glycosaminoglycans (GAGs) level and reduce inflammatory markers in diabetic human aortic endothelial cells (HAECs).

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?