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SML0235 Sigma-Aldrich

CDPPB

≥98% (HPLC)

Synonym: 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide

  • CAS Number 781652-57-1

  • Empirical Formula (Hill Notation) C23H16N4O

  • Molecular Weight 364.40

  •  PubChem Substance ID 329825248

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Description

Application

CDPPB may be used in mGluR5-mediated cell signaling studies.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.

CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Making Headway

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Protocols & Articles
Peer-Reviewed Papers
15

References

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