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SML0246 Sigma-Aldrich

Tirofiban hydrochloride monohydrate

≥98% (HPLC)

Synonym: L 700462, MK 383, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine

  • CAS Number 150915-40-5

  • Empirical Formula (Hill Notation) C22H36N2O5S·HCl·H2O

  • Molecular Weight 495.07

  •  MDL number MFCD07368623

  •  PubChem Substance ID 329825256

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytoskeleton and Extracellular Matrix,
InChI Key   HWAAPJPFZPHHBC-FGJQBABTSA-N
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D -10 to -18° (c=1, MeOH)
storage condition   desiccated
color   white to beige
solubility   DMSO: >12 mg/mL at warmed to 60 °C
shipped in   wet ice
storage temp.   −20°C

Description

Application

Tirofiban hydrochloride monohydrate has been used as an αIIbβ3 integrin (glycoprotein IIb/IIIa) inhibitor for mouse induced pluripotent stem cell (iPSC) culture.

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Tirofiban hydrochloride is a potent non-peptide, glycoprotein IIb/IIIa inhibitor. Blocks platelet aggregation and thrombus formation.

Tirofiban might cause thrombocytopenia.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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