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SML0273 Sigma-Aldrich

VAS2870

≥97% (HPLC)

Synonym: 1,3-Benzoxazol-2-yl-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl sulfide, 7-(1,3-Benzoxazol-2-ylsulfanyl)-3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine, 7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine, VAS 2870, VAS-2870

  • CAS Number 722456-31-7

  • Empirical Formula (Hill Notation) C18H12N6OS

  • Molecular Weight 360.39

  •  MDL number MFCD03407188

  •  PubChem Substance ID 329825281

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Nitric Oxide Metabolism,
Quality Level   100
assay   ≥97% (HPLC)
form   powder
color   white to beige
solubility   DMSO: ≥5 mg/mL
storage temp.   room temp
SMILES string   C(c1ccccc1)n2nnc3c(Sc4nc5ccccc5o4)ncnc23
InChI   1S/C18H12N6OS/c1-2-6-12(7-3-1)10-24-16-15(22-23-24)17(20-11-19-16)26-18-21-13-8-4-5-9-14(13)25-18/h1-9,11H,10H2
InChI key   HZSOKHVVANONPV-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

VAS2870 is a cell-permeable and specific NADPH oxidase (NOX) inhibitor that effectively suppresses growth factor-mediated ROS liberation in VSMC.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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