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SML0285 Sigma-Aldrich

Pleuromutilin

≥95%

Synonym: Drosophilin B, Mutilin 14-glycolate, NSC 121145

  • CAS Number 125-65-5

  • Empirical Formula (Hill Notation) C22H34O5

  • Molecular Weight 378.50

  •  EC Number 204-747-5

  •  PubChem Substance ID 329825293

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood,
InChI Key   ZRZNJUXESFHSIO-BKUNHTPHSA-N
assay   ≥95%
form   powder
optical activity   [α]/D +30 to +40° (c=1; CH2Cl2)
color   white to beige
solubility   DMSO: >10 mg/mL (warmed)
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.

Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
MC5408000

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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