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SML0302 Sigma-Aldrich

4-CMTB

≥98% (HPLC)

Synonym: 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide

  • CAS Number 300851-67-6

  • Empirical Formula (Hill Notation) C14H15ClN2OS

  • Molecular Weight 294.80

  •  MDL number MFCD02666163

  •  PubChem Substance ID 329825307

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   DMSO: ≥10 mg/mL
storage temp.   2-8°C
SMILES string   CC(C)C(C(=O)Nc1nccs1)c2ccc(Cl)cc2
InChI   1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)
InChI key   AZYDQCGCBQYFSE-UHFFFAOYSA-N

Description

Application

4-CMTB has been used as an allosteric agonist for the free fatty acid receptor 2 (FFAR2) in human lung carcinoma (A549) cells for cell viability assay and Influenza A virus (IAV) internalization studies.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

4-CMTB is a phenylacetamide compound that acts as an allosteric modulator for the activity of short-chain fatty acid ligand in the FFA2 receptor.

4-CMTB is a potent allosteric agonist of free fatty acid receptor 2 (FFA2).

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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