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SML0321 Sigma-Aldrich

Cyamemazine

≥98% (HPLC)

Synonym: 10-[3-(Dimethylamino)-2-methylpropyl]-10H-phenothiazine-2-carbonitrile, 7204 R. E., 7204 RP, Ciamatil, Cianatil, Cyamemazin, R.P. 7204, TH 2602

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   light yellow to yellow-green
solubility   DMSO: ≥5 mg/mL
storage temp.   2-8°C
SMILES string   CC(CN(C)C)CN1c2ccccc2Sc3ccc(cc13)C#N
InChI   1S/C19H21N3S/c1-14(12-21(2)3)13-22-16-6-4-5-7-18(16)23-19-9-8-15(11-20)10-17(19)22/h4-10,14H,12-13H2,1-3H3
InChI key   SLFGIOIONGJGRT-UHFFFAOYSA-N

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Cyamemazine belongs to the class of phenothiazine drugs. It is known to treat severe depression, schizophrenia and bipolar disorder.

Cyamemazine is a potent antagonist of 5-HT2C and 5-HT3 receptors with antipsychotic and anxiolytic properties.

Safety & Documentation

Safety Information

Symbol 
GHS09  GHS09
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Serotonin Receptors

Serotonin (5-hydroxytryptamine, 5-HT) is widely distributed throughout the mammalian body, being synthesized from L-tryptophan in enterochromaffin cells of the gastro-intestinal tract as well as in s...
Keywords: Active transport, Atomic absorption spectroscopy, Cancer, Clinical, Gene expression, Ligands, Neurotransmitters, Obesity, Polymorphisms, Schizophrenia, Transduction

Peer-Reviewed Papers
15

References

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