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SML0338 Sigma-Aldrich

Lornoxicam

≥98% (HPLC)

Synonym: 6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, Chlortenoxicam, Ro 13-9297, TS 110

  • CAS Number 70374-39-9

  • Empirical Formula (Hill Notation) C13H10ClN3O4S2

  • Molecular Weight 371.82

  •  MDL number MFCD00866163

  •  PubChem Substance ID 329825343

  •  NACRES NA.77

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Properties

Related Categories Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   faintly yellow to dark yellow
solubility   DMSO: >5 mg/mL (warmed)
storage temp.   −20°C
SMILES string   CN1C(C(=O)Nc2ccccn2)=C(O)c3sc(Cl)cc3S1(=O)=O
InChI   1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChI key   WLHQHAUOOXYABV-UHFFFAOYSA-N

Description

General description

Lornoxicam belongs to the oxicam class. It has anti-inflammatory and antipyretic properties. Lornoxicam prevents the synthesis of prostaglandin (PG) by inhibiting cyclo-oxygenase. It is used to relieve various types of symptoms associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica and low back pain.

Application

Lornoxicam has been used as a drug in melanin binding study with cassette dosing and rapid equilibrium dialysis inserts.

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Lornoxicam is an oxicam-class NSAID with strong analgesic properties.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
WGK 3
RTECS 
XJ9095000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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