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SML0351 Sigma-Aldrich

CPDT

≥96% (HPLC)

Synonym: 5,6-Dihydro-Cyclopenta[c]-1,2-dithiole-3(4H)-thione, CJ 11788, SNU2A

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Properties

Related Categories Antioxidants and Cytoprotectants, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology,
Quality Level   100
assay   ≥96% (HPLC)
form   powder
color   faintly red to very dark red
solubility   DMSO: 2 mg/mL (warmed)
storage temp.   2-8°C
SMILES string   S=C1SSC2=C1CCC2
InChI   1S/C6H6S3/c7-6-4-2-1-3-5(4)8-9-6/h1-3H2
InChI key   AVSGTGUIBQOXJK-UHFFFAOYSA-N

Description

Application

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) has been used to study its protective effects and the underlying mechanism in diabetic cardiomyopathy.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

5,6-dihydrocyclopenta-1,2-dithiole-3-thione (CPDT) is a phase II enzyme inducer. It exhibits protective actions against chemical carcinogens.

CPTD (SNU2A) is a cytoprotective agent that protects mitochondria during cell stress by increasing antioxidant capacity. CPTD inhibits phosphorylation and activation of Fyn, which maintains AMPK activity and activation of Nrf2.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3413B 6.1 / PGIII
WGK Germany 
WGK 2

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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