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SML0375 Sigma-Aldrich

CID 5951923

≥98% (HPLC)

Synonym: 3-(3-Nitrophenyl)-2-propenoic acid 2-[methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl ester, AC1NZ6UQ, [2-[(1,1-Dioxothiolan-3-yl)-methylamino]-2-oxoethyl] (E)-3-(3-nitrophenyl)prop-2-enoate

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 10 mg/mL (clear solution)
storage temp.   room temp
SMILES string   CN(C1CCS(=O)(=O)C1)C(=O)COC(=O)\C=C\c2cccc(c2)[N+]([O-])=O
InChI   1S/C16H18N2O7S/c1-17(14-7-8-26(23,24)11-14)15(19)10-25-16(20)6-5-12-3-2-4-13(9-12)18(21)22/h2-6,9,14H,7-8,10-11H2,1H3/b6-5+
InChI key   URVRJYLSUVXWBC-AATRIKPKSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CID 5951923 is an inhibitor of Kruppel-like factor 5 (KLF5) expression that significantly reduced endogenous KLF5 protein levels and decreased viability of several colorectal cancer cell lines. CID 5951923 is selective for colon cancer cells over nontransformed cells.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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