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SML0409 Sigma-Aldrich

STF-083010

≥98% (HPLC)

Synonym: N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation,
InChI Key   TVIVJHZHPKNDAQ-MHWRWJLKSA-N
assay   ≥98% (HPLC)
form   powder
color   light yellow to yellow-green
solubility   DMSO: 5 mg/mL (clear solution)
storage temp.   −20°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

STF-083010 is a potent inhibitor of the ER transmembrane protein IRE1, which mediates the unfolded protein response. STF-083010 inhibits IRE1 endonuclease and mRNA splicing activity in response to endopasmic reticulum (ER) stress, but has no affect on the kinase activity of IRE1.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Milli-Q® Water Purification Solutions
Protocols & Articles
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