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SML0473 Sigma-Aldrich

Noladin ether

≥98% (HPLC)

Synonym: 2-Arachidonylglyceryl ether, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yloxy]-1,3-propanediol; 2-AG ether, HU 310

  • CAS Number 222723-55-9

  • Empirical Formula (Hill Notation) C23H40O3

  • Molecular Weight 364.56

  •  EC Number 200-578-6

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cannabinoids, Cell Biology, Cell Signaling and Neuroscience,
assay   ≥98% (HPLC)
form   ethanol solution (10 mg/mL (1% w/v))
drug control   regulated under CDSA - not available from Sigma-Aldrich Canada
color   colorless to light yellow
shipped in   dry ice
storage temp.   −70°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany 
2
Flash Point(F) 
57.2 °F
Flash Point(C) 
14 °C

Documents

Certificate of Analysis (COA)

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