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SML0643 Sigma-Aldrich

M617 trifluoroacetate salt

≥95% (HPLC)

Synonym: Galanin(1-13)-Gln14-bradykinin(2-9)amide trifluoroacetate salt

  • CAS Number 860790-38-1 (free base)

  • Empirical Formula (Hill Notation) C112H161N29O28 · xC2HF3O2

  • Molecular Weight 2361.65 (free base basis)

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Galanins,
Quality Level   100
assay   ≥95% (HPLC)
form   powder
color   white to beige
shipped in   wet ice
storage temp.   −20°C

Description

Amino Acid Sequence

GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLN-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-NH2 trifluoroacetate salt

Packaging

1 mg in glass bottle

Biochem/physiol Actions

M617, galanin(1–13)-Gln14-bradykinin(2–9)amide, is a chimeric peptide that acts as a selective agonist for the Galanin GalR1 receptor. M617 shows 25-fold specificity for GalR1with Ki values of 0.23 for GAL1 and 5.71 nM for GAL2.

Features and Benefits

This compound is featured on the Galanin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Galanin Receptors

Galanin is a 30 amino acid non-amidated peptide in humans and identified in 14 other species as a 29 amino acid C-terminally amidated peptide. Galanin is widely distributed in both the central and pe...
Keywords: Anti-depressants, Anticonvulsants, Apoptosis, Atomic absorption spectroscopy, Gene expression, Hormones, Ligands, Metabolites, Neurotransmitters, Reductions, Transduction

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