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SML0679 Sigma-Aldrich

Danshensu sodium salt

≥98% (HPLC)

Synonym: (R)-α,3,4-Trihydroxy-benzenepropanoic acid sodium salt, (R)-(+)-3-(3,4-Dihydroxyphenyl)lactic acid, 3-(3′,4′-Dihydroxyphenyl)-(2R)-lactic acid sodium salt, DS 182, Dan Shen Su, Dan shen suan A, Salianic acid A, Salvianic acid A

  • CAS Number 81075-52-7

  • Empirical Formula (Hill Notation) C9H9O5 · Na

  • Molecular Weight 220.15

  •  MDL number MFCD07781415

  •  PubChem Substance ID 329825582

  •  NACRES NA.77

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Properties

Related Categories Akt, Antioxidants and Cytoprotectants, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D +30 to +40°, c = 1 in H2O
color   white to beige
solubility   H2O: 20 mg/mL, clear
storage temp.   2-8°C
SMILES string   OC1=C(O)C=CC(C[C@@H](O)C([O-])=O)=C1.[Na+]
InChI   1S/C9H10O5.Na/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14;/h1-3,8,10-12H,4H2,(H,13,14);/q;+1/p-1/t8-;/m1./s1
InChI key   ZMMKVDBZTXUHFO-DDWIOCJRSA-M

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia. Danshensu is cardioprotective, which protects myocardium from the reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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