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SML0713 Sigma-Aldrich

2′-C-Methylguanosine

≥98% (HPLC)

Synonym: 2′-C-Methyl-guanosine, 2-C′-MeG

  • CAS Number 374750-30-8

  • Empirical Formula (Hill Notation) C11H15N5O5

  • Molecular Weight 297.27

  •  NACRES NA.77

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Properties

Related Categories AIDS and Viral Research Reagents, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   H2O: 5 mg/mL, clear (warmed)
storage temp.   −20°C

Description

Application

2′-C-Methylguanosine has been used as reference inhibitor to study cytotoxicity.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

2′-C-Methylguanosine (2’-MeG) is a potent and specific RNA dependent RNA polymerase NS5B inhibitor of the hepatitis C virus (HCV).

2′-C-methylguanosine is also known as BMS-986094. This prodrug is used for the treatment of chronic hepatitis C virus infection.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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