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SML0799 Sigma-Aldrich

CYM 50179

≥98% (HPLC)

Synonym: 2,6-Dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-pyridine, CYM50179

  • CAS Number 1355026-47-9

  • Empirical Formula (Hill Notation) C13H9Br2Cl2NO2

  • Molecular Weight 441.93

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 15 mg/mL, clear
storage temp.   −20°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CYM50179 is a potent, selective agonist of the sphingosine-1-phosphate receptor 4 (S1P4). CYM50179 activates S1P4 with an IC50 of 46 nM, with no affect on other S1P receptors at concentrations up to 25 μM.

Features and Benefits

This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Lysophospholipid Receptors

Although historically considered as intermediates in the biosynthesis of glycerophospholipids and the degradation of sphingolipids, the lysophospholipids lysophosphatidic acid (LPA) and sphingosine 1...
Keywords: Atomic absorption spectroscopy, Cancer, Chemical biology, Degradations, Gene expression, Genetic, Genetics, Ligands, Phosphorylations, Transduction

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