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SML0858 Sigma-Aldrich

SC-1

≥98% (HPLC)

Synonym: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[4-(4-cyanophenoxy)phenyl]-urea

  • CAS Number 1313019-65-6

  • Empirical Formula (Hill Notation) C21H13ClF3N3O2

  • Molecular Weight 431.80

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Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

SC-1 is a derivative of the multiple tyrosine kinase inhibitor sorafenib with no kinase-inhibition activity. SC-1 blocks STAT3 phosphorylation and activation with similar potency to sorafenib, and induces apoptosis in hepatocellular carcinoma cell lines.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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