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SML0859 Sigma-Aldrich

WDR5-0103

≥98% (HPLC)

Synonym: 3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-benzoic acid methyl ester, Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate

  • CAS Number 890190-22-4

  • Empirical Formula (Hill Notation) C21H25N3O4

  • Molecular Weight 383.44

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DNA-RNA Transcription Regulators,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 10 mg/mL, clear
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

WDR5-0103 is a WD40-repeat antagonist that binds to WDR55 central cavity. WDR5-0103 inhibits MLL1 histone methyltransferase activity in vitro through disruption of the interaction of MLL with WDR5.

Safety & Documentation

Safety Information

Symbol 
GHS09  GHS09
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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