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SML1019 Sigma-Aldrich

Lofexidine hydrochloride

≥98% (HPLC)

Synonym: 2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole hydrochloride, Baq 168, Britlofex, Lofetensin, Loxacor, MDL 14042

  • CAS Number 21498-08-8

  • Empirical Formula (Hill Notation) C11H12Cl2N2O · HCl

  • Molecular Weight 295.59

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Imidazoline Binding Site Ligands,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   H2O: 20 mg/mL, clear
storage temp.   2-8°C
InChI   1S/C11H12Cl2N2O.ClH/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13;/h2-4,7H,5-6H2,1H3,(H,14,15);1H
InChI key   DWWHMKBNNNZGHF-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Lofexidine, a derivative of clonidine, is a very potent agonist of α2 adrenoceptors. Lofexidine is used as a treatment for withdrawl from heroin and other opiates, and as a short-activg anti-hypertensive agent.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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