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SML1042 Sigma-Aldrich

Eptifibatide acetate

≥98% (HPLC)

Synonym: Cyclo(S,S)-Mpr(Har)GDWPC-NH2 acetate, N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate

  • CAS Number 881997-86-0

  • Empirical Formula (Hill Notation) C35H49N11O9S2 · xC2H4O2

  • Molecular Weight 831.96 (free base basis)

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Properties

Related Categories Anticoagulants, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Blood, Cell Biology,
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   H2O: 2 mg/mL, clear (warmed)
shipped in   wet ice
storage temp.   −20°C

Description

General description

Eptifibatide acetate is a cyclic heptapeptide. It is the member of the class arginin-glycin-aspartat-mimetics. Eptifibatide has a short half-life. The drug decreases the risk of myocardial infarction (MI). Eptifibatide acetate might be associated with thrombocytopenia.

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor, preventing platelet aggregation. Eptifibatide binds reversibly and competitively.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Immunology Research

The immune system is a complex network to detect and defend against non-self pathogenic agents, such as disease-causing viruses, bacteria, and other microorganisms. Various signaling pathways contrib...
Keywords: Antibiotics, Antifungals, Antivirals, Apoptosis, Bioactive small molecules, Cell signaling, Diabetes, Diseases, Immunology, Inflammation

Peer-Reviewed Papers
15

References

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