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SML1078 Sigma-Aldrich

4-Bromo-Resveratrol

≥98% (HPLC)

Synonym: 5-[(1E)-2-(4-Bromophenyl)ethenyl]-1,3-benzenediol

  • CAS Number 1224713-90-9

  • Empirical Formula (Hill Notation) C14H11BrO2

  • Molecular Weight 291.14

  •  MDL number MFCD00238583

  •  PubChem Substance ID 329825458

  •  NACRES NA.77

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Properties

Related Categories Antioxidants and Cytoprotectants, B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
storage condition   protect from light
color   , white to yellow to brown
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C
SMILES string   OC1=CC(/C=C/C2=CC=C(Br)C=C2)=CC(O)=C1
InChI   1S/C14H11BrO2/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,16-17H/b2-1+
InChI key   NCJVLKFAQIWASE-OWOJBTEDSA-N

Description

General description

4-Bromo-Resveratrol blocks the activity of human sirtuin 1 (sirt1) and sirt3 by binding to C-site and another active site pocket.

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

4-Bromo-Resveratrol is a resveratrol analog that potently inhibits Sirt1 and Sirt3.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

light sensitive

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Gene Regulation

The loss of regulation of gene expression is a key component to many human disease states, including neurodegenerative disorders, autoimmune conditions and, most prominently, cancers. Regulation of g...
Keywords: Acetylations, Epigenetics, Gene expression, Genomics, Methylations, PAGE, Post translational modifications, Transcription

Peer-Reviewed Papers
15

References

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