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SML1266 Sigma-Aldrich

Bryostatin 2

≥95% (HPLC)

Synonym: (+)-Bryostatin 2, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-Tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-

  • CAS Number 87745-28-6

  • Empirical Formula (Hill Notation) C45H66O16

  • Molecular Weight 863.00

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Properties

Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
biological source   Bugula neritina (sponge)
assay   ≥95% (HPLC)
form   film
color   colorless to light yellow
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

10 μg in glass bottle

Biochem/physiol Actions

Bryostatin 2 is potent protein kinase C activator (Ki = 5.9 nM) and an antagonist to phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA). Bryostatin 2 exhibits antineoplastic activity against the murine P388 lymphocytic leukemia and human U937 cells.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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