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SML1267 Sigma-Aldrich

Bryostatin 3

≥95% (HPLC)

Synonym: [4S-[4R*(2E,4E),5R*,7E,9S*,11Z,13R*,15R*,17R*,19S*,21S*,25S*(S*),27S*,27aR*]]-2,4-Octadienoic acid,17-(acetyloxy)-4,5,6,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-(1-hydroxyethyl)-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl ester

  • CAS Number 143370-84-7

  • Empirical Formula (Hill Notation) C46H64O17

  • Molecular Weight 888.99

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Properties

Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
biological source   Bugula neritina (sponge)
assay   ≥95% (HPLC)
form   film
color   colorless to light yellow
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

10 μg in glass bottle

Biochem/physiol Actions

Bryostatin 3 is a potent protein kinase C activator with a Ki of 2.75 nM, and an antagonist to phorbol ester tumor promoter TPA. Bryostatin 3 is isolated from the bryozoan Bugula neritina.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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