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SML1399 Sigma-Aldrich

CCT031374 hydrobromide

≥98% (HPLC)

Synonym: 1-[1,1′-Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide

  • CAS Number 1219184-91-4

  • Empirical Formula (Hill Notation) C23H19N3O · HBr

  • Molecular Weight 434.33

  •  MDL number MFCD06737234

  •  PubChem Substance ID 329825847

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   DMSO: 10 mg/mL, clear
storage temp.   2-8°C
SMILES string   O=C(C1=CC=C(C2=CC=CC=C2)C=C1)CN3C4=C(C=CC=C4)N5C3=NCC5.[H]Br
InChI   1S/C23H19N3O.BrH/c27-22(19-12-10-18(11-13-19)17-6-2-1-3-7-17)16-26-21-9-5-4-8-20(21)25-15-14-24-23(25)26;/h1-13H,14-16H2;1H
InChI key   MPILENOYNNNGKO-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CCT031374 is an inhibitor of TCF-dependent transcription. CCT031374 is a selective β-catenin signaling inhibitor that decreases the intracellular/soluble β-cat level. CCT031374 inhibits  proliferation of numberous cancer cell lines by induction of apoptosis.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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