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SML1418 Sigma-Aldrich

AC187 trifluoroacetate salt

≥95% (HPLC)

Synonym: AC 187, AC-187, Ac-VLGKLSQELHKLQTYPRTNTGSNTY-NH2, Ac-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Asn-Thr-Tyr-NH2, N-Acetyl-30-L-asparagine-32-L-tyrosinamide-8-32-calcitonin (salmon)

  • CAS Number 151804-77-2 (free base)

  • Empirical Formula (Hill Notation) C127H205N37O40 · xC2HF3O2

  • Molecular Weight 2890.21 (free base basis)

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Properties

Related Categories A-AM, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥95% (HPLC)
form   powder
color   white to off-white
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

1 mg in glass bottle

Biochem/physiol Actions

AC187 is an orally active, potent and selective amylin receptor antagonist that increases glucagon secretion, alters plasma glucose levels and increases food intake in vivo. AC187 completely blocks internalization of amylin monomers in pancreatic cells. AC187 blocks β-amyloid neurotoxicity in rats.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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