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SML1470 Sigma-Aldrich

PACA

≥98% (HPLC)

Synonym: 3-(3,4-Dihydroxyphenyl)-N-2-propyn-1-yl-2-propenamide

  • CAS Number 1431724-30-9

  • Empirical Formula (Hill Notation) C12H11NO3

  • Molecular Weight 217.22

  •  PubChem Substance ID 329825904

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation,
InChI Key   HLHSUNWAPXINQU-GQCTYLIASA-N
assay   ≥98% (HPLC)
form   powder
color   white to light brown
solubility   DMSO: 25 mg/mL, clear
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

PACA is a potentiator of NGF-induced neurite outgrowth that attenuates 6-hydroxydopamine (6-OHDA) neurotoxicity in dopaminergic PC12 cells. PACA induced the nuclear translocation of transcription factor Nrf2 and the expression of antioxidant heme oxygenase-1 (HO-1).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


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Protocols & Articles
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