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SML1471 Sigma-Aldrich

SN50 trifluoroacetate salt

≥95% (HPLC)

Synonym: AAVALLPAVLLALLAPVQRKRQKLMP trifluoroacetate salt, H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH trifluoroacetate salt, NF-KB SN50 cell permeable inhibitory peptide trifluoroacetate salt, Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt

  • CAS Number 213546-53-3 (free base)

  • Empirical Formula (Hill Notation) C129H230N36O29S · xC2HF3O2

  • Molecular Weight 2781.50 (free base basis)

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Gene Regulation,
assay   ≥95% (HPLC)
form   film
color   white
shipped in   wet ice
storage temp.   −20°C

Description

Packaging

1 mg in glass bottle

Biochem/physiol Actions

SN50 is an NF-KB cell permeable inhibitory peptide. The SN50 sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-KB p50 linked to a peptide cell-permeabilization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 Peptide inhibits translocation of the NF-KB active complex into the nucleus.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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