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SML1508 Sigma-Aldrich

C-DIM12

≥98% (HPLC)

Synonym: 3,3′-[(4-Chlorophenyl)methylene]bis-1H-indole, 4-Chlorophenyldi-3-indolylmethane, 4-Chlorophenyl-3,3′-diindolylmethane

  • CAS Number 178946-89-9

  • Empirical Formula (Hill Notation) C23H17N2Cl

  • Molecular Weight 356.85

  •  PubChem Substance ID 329825927

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
storage condition   protect from light
color   , light orange to dark red
solubility   DMSO: 20 mg/mL, clear
storage temp.   2-8°C
SMILES string   ClC(C=C1)=CC=C1C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5
InChI   1S/C23H17ClN2/c24-16-11-9-15(10-12-16)23(19-13-25-21-7-3-1-5-17(19)21)20-14-26-22-8-4-2-6-18(20)22/h1-14,23,25-26H
InChI key   LTLRXTDMXOFBDW-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

C-DIM12 is a potent and selective nuclear receptor Nurr1 (NR4A2) activator that activates Nurr1 in urothelial carcinoma cells and in pancreatic cells. C-DIM12 suppresses inflammatory signaling in microglia.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
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