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SML1521 Sigma-Aldrich

Irsogladine maleate

≥98% (HPLC)

Synonym: 2,4-Diamino-6-(2,5-dichlorophenyl)-s-triazine maleate, 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine (2Z)-2-butenedioate (1:1), Gaslon N, MN 1695

  • CAS Number 84504-69-8

  • Empirical Formula (Hill Notation) C9H7Cl2N5 ·C4H4O4

  • Molecular Weight 372.16

  •  MDL number MFCD00865153

  •  PubChem Substance ID 329825938

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 15 mg/mL, clear
storage temp.   room temp
SMILES string   C[C@]1([H])[C@@](C)(O)CC2=C(C(OC)=C(OC)C(OC)=C2)C3=C(OC)C4=C(OCO4)C=C3C1
InChI   1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3/t12-,23-/m0/s1
InChI key   ZWRRJEICIPUPHZ-MYODQAERSA-N

Description

Packaging

50 mg in glass bottle

Biochem/physiol Actions

Irsogladine maleate is an inhibitor of phosphodiesterase 4 (PDE4) with gastroprotective activity. Irsogladine maleate is a mucosal protective drug with a number of activites including facilitation of gap junctional intercellular communication, inhibition of the reduced gastric mucosal blood flow response, and suppression of reactive oxygen species (ROS) production.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
XY5930000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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