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SML1522 Sigma-Aldrich

Doxofylline

≥98% (HPLC)

Synonym: 7-(1,3-Dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione, 7-(1,3-Dioxolan-2-ylmethyl)theophylline

  • CAS Number 69975-86-6

  • Empirical Formula (Hill Notation) C11H14N4O4

  • Molecular Weight 266.25

  •  MDL number MFCD00865218

  •  PubChem Substance ID 329825939

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cyclic Nucleotide Metabolism,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   H2O: 2 mg/mL, clear (warmed)
storage temp.   2-8°C
SMILES string   CN1C2=C(N(CC3OCCO3)C=N2)C(N(C)C1=O)=O
InChI   1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
InChI key   HWXIGFIVGWUZAO-UHFFFAOYSA-N

Description

General description

Doxofylline is a novel xanthine derivative comprising of dioxolone group.

Packaging

50 mg in glass bottle

Biochem/physiol Actions

Doxofylline (also known as doxophylline) has antitussive and bronchodilator effects. Doxofylline is used clinically in the treatment of asthma. Doxofylline has similar efficacy to theophylline, but unlike theophylline or other xanthines has little affinity for adenosine receptors and does not produce stimulant effects and has significantly fewer side effects.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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