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SML1624 Sigma-Aldrich

JNJ-63533054

≥98% (HPLC)

Synonym: (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl)benzamide

  • CAS Number 1802326-66-4

  • Empirical Formula (Hill Notation) C17H17ClN2O2

  • Molecular Weight 316.78

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, G Protein Function,
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D -89 to -99°, c = 1 in ethanol
color   white to beige
solubility   DMSO: 20 mg/mL, clear
storage temp.   room temp

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

JNJ-63533054 is a potent and selective agonist of the orphan receptor hGPR139, a GPCR receptor expressed in the brain in circumventricular regions of the habenula and septum. JNJ-63533054 has an EC50 value of 16 nM, crosses the blood-brain barrier, and is orally available.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Protocols & Articles
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