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SML1721 Sigma-Aldrich

Vedaprofen

≥98% (HPLC)

Synonym: (±)-2-(4-Cyclohexylnaphthalen-1-yl)propionic acid

  • CAS Number 71109-09-6

  • Empirical Formula (Hill Notation) C19H22O2

  • Molecular Weight 282.38

  •  Beilstein/REAXYS Number 5568831

  •  EC Number 275-196-6

  •  MDL number MFCD00866019

  •  NACRES NA.77

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Properties

Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
shipped in   wet ice
storage temp.   −20°C
SMILES string   CC(C(O)=O)c1ccc(C2CCCCC2)c3ccccc13
InChI   1S/C19H22O2/c1-13(19(20)21)15-11-12-16(14-7-3-2-4-8-14)18-10-6-5-9-17(15)18/h5-6,9-14H,2-4,7-8H2,1H3,(H,20,21)
InChI key   VZUGVMQFWFVFBX-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Vedaprofen is a non-steroidal anti-inflammatory drug (NSAID) that has been found to have antimicrobial activity. Vedaprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition, while its antimicrobial activity is less certain. Vedaprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown vedaprofen can target the Escherichia coli DNA polymerase III β subunit.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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