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SML1783 Sigma-Aldrich

BAY-364

≥98% (HPLC)

Synonym: 6-(3-Hydroxypropyl)-2-(1-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione, BAY-299N

  • Empirical Formula (Hill Notation) C23H19N3O4

  • Molecular Weight 401.41

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Properties

Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
assay   ≥98% (HPLC)
form   powder
color   white to light brown
solubility   DMSO: 5 mg/mL, clear (warmed)
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

BAY-364 (BAY-299N) is structurally similar to selective BRD1/TAF1 inhibitor BAY-299 and serves as inactive control. BAY-364 is inactive against BRD1 and exhibit moderate activity against TAF1 (3 μM). For full characterization details of the active probe, please visit the BAY-299 probe summary on the Structural Genomics Consortium (SGC) website.

BAY-299, the active probe, is available from Sigma. To learn more about and purchase BAY-299, click here.

To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc

Features and Benefits

BAY-364 is a negative control for BAY-299, an epigenetic chemical probe available through a partnership between Sigma Life Science and the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Gene Regulation

The loss of regulation of gene expression is a key component to many human disease states, including neurodegenerative disorders, autoimmune conditions and, most prominently, cancers. Regulation of g...
Keywords: Acetylations, Epigenetics, Gene expression, Genomics, Methylations, PAGE, Post translational modifications, Transcription

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