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SML1856 Sigma-Aldrich

8-Aminoguanine

≥95% (HPLC)

Synonym: 2,8-Diamino-1,9-dihydro-6H-purin-6-one; 2,8-Diamino-hypoxanthine, NSC 23170

  • CAS Number 28128-41-8

  • Empirical Formula (Hill Notation) C5H6N6O

  • Molecular Weight 166.14

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Properties

Related Categories 0-9, A-AM, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   ≥95% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   0.1 M NaOH: 2 mg/mL, clear (warmed)
storage temp.   2-8°C
SMILES string   O=C1C2=C(N=C(N)N2)NC(N)=N1
InChI   1S/C5H6N6O/c6-4-8-1-2(9-4)10-5(7)11-3(1)12/h(H6,6,7,8,9,10,11,12)
InChI key   WYDKPTZGVLTYPG-UHFFFAOYSA-N

Description

Packaging

25 mg in glass bottle

Biochem/physiol Actions

8-Aminoguanine, a guanine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic that increased sodium excretion by 17.2-fold and decrease potassium excretion by 71.0%. 8-Aminoguanine increases glucose excretion by 12.1-fold. Also, 8-Aminoguanine suppressed deoxycorticosterone/salt-induced hypertension.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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