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SML2088 Sigma-Aldrich

Procainamide hydrochloride

≥98% (HPLC)

Synonym: 4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide, Amidoprocaine, Amisalin, Cardiorytmin, HC 5006, Novocaine amide hydrochloride, Novocamid hydrochloride, Procainamide hydrochloride, Procainamide monohydrochloride, Procamid, Procamide, Procan SR, Procapan, Procardyl, Pronestyl hydrochloride, Pronestyl, Spicain amide

  • CAS Number 614-39-1

  • Linear Formula H2NC6H4CONHCH2CH2N(C2H5)2·HCl

  • Molecular Weight 271.79

  •  Beilstein/REAXYS Number 3729517

  •  EC Number 210-381-7

  •  MDL number MFCD00012998

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, PI-PZ
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
mp   167-169 °C (lit.)
solubility   H2O: 2 mg/mL, clear
storage temp.   2-8°C
SMILES string   Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1
InChI   1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H
InChI key   ABTXGJFUQRCPNH-UHFFFAOYSA-N
Gene Information   human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

Biochem/physiol Actions

Procainamide hydrochloride is a sodium channel blocker and Class IA anti-arrhythmic. It has also been shown to Inhibit DNA methyltransferase and modulate epigenetic regulation of gene expression.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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