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SML2213 Sigma-Aldrich

CPI-637

≥98% (HPLC)

Synonym: (4R)-1,3,4,5-Tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-2H-1,5-benzodiazepin-2-one, (4R)-4-Methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one, 2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-4-methyl-6-[1-methyl-3-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-5-yl]-, (4R)-, CPI 637

  • CAS Number 1884712-47-3

  • Empirical Formula (Hill Notation) C22H22N6O

  • Molecular Weight 386.45

  •  MDL number MFCD30489741

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D -39 to -49°, c = 1.0 in chloroform-d
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   −20°C

Description

Biochem/physiol Actions

CPI-637 is a cell penetrant, selective and potent CBP/p300 bromodomain inhibitor.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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