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SML2235 Sigma-Aldrich

CL075

≥98% (HPLC)

Synonym: 2-Propylthiazolo[4,5-c]quinolin-4-amine, 3M002

  • CAS Number 256922-53-9

  • Empirical Formula (Hill Notation) C13H13N3S

  • Molecular Weight 243.33

  •  MDL number MFCD09998898

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C

Description

Biochem/physiol Actions

CL075 is a selective agonist of Toll-like receptor-8 (TLR-8) with immunostimulant activity. It showed an EC50 value of 400nM for IRF-NFΚB stimulation in TLR8 compared to 4 μM for TLR7.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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