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SML2252 Sigma-Aldrich

TP053

≥98% (HPLC)

Synonym: N-Methyl-6-nitro-2-phenylthieno[2,3-d]pyrimidin-4-amine

  • CAS Number 1613295-96-7

  • Empirical Formula (Hill Notation) C13H10N4O2S

  • Molecular Weight 286.31

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Properties

assay   ≥98% (HPLC)
form   powder
color   yellow to orange
solubility   DMSO: 2 mg/mL, clear (warmed)
storage temp.   2-8°C

Description

Biochem/physiol Actions

TP053 is a potent thienopyrimidine antitubercular agent that kills both replicating and nonreplicating Mycobacterium tuberculosis. It appears that TP053 is a prodrug, which is activated by mycothiol-dependent reductase Rv2466c.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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