EMAIL THIS PAGE TO A FRIEND
SML2254 Sigma-Aldrich

J-113397

≥98% (HPLC)

Synonym: 1-[(3R,4R)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one

  • CAS Number 256640-45-6

  • Empirical Formula (Hill Notation) C24H37N3O2

  • Molecular Weight 399.57

  •  MDL number MFCD04113003

Purchase

Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, J
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D +7 to +10°, c = 1 in isopropanol
storage condition   desiccated
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   room temp

Description

Biochem/physiol Actions

J-113397 is an antagonist of NOP, the nociceptin/orphanin FQ (N/OFQ) receptor. J-113397 exhibited an IC50 value of 2.3 nM in Chinese hamster ovary (CHO) cells expressing ORL1 receptor showed with 600-fold or less affinity for μ-, δ- and κ-opioid receptors.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?