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SML2466 Sigma-Aldrich

OXFBD04

≥98% (HPLC)

Synonym: 3-(3,5-dimethylisoxazol-4-yl)-5-(hydroxy(pyridin-3-yl)methyl)phenol

  • Empirical Formula (Hill Notation) C17H16N2O3

  • Molecular Weight 296.32

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, O
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C
SMILES string   CC1=NOC(C)=C1C2=CC(C(O)C3=CN=CC=C3)=CC(O)=C2

Description

Biochem/physiol Actions

OXFBD04 is a potent and selective inhibitor of BRD4(1) that inhibits interactions of BRD4with the RelA subunit of NF-κB. OXFBD02 inhibits proliferation of various cancer cell lines including leukaemia, breast, and renal cancer cell lines.

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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