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SML2535 Sigma-Aldrich

MRK-740

≥98% (HPLC)

Synonym: 4-(3-(3,5-Dimethoxy-phenyl)-1,2,4-oxadiazol-5-yl)-1-methyl-9-(2-methyl-pyridin-4-yl)-1,4,9-triaza-spiro[5.5]undecane

  • CAS Number 2387510-80-5

  • Empirical Formula (Hill Notation) C25H32N6O3

  • Molecular Weight 464.56

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, M
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear
storage temp.   2-8°C
SMILES string   CN1CCN(C2=NC(C3=CC(OC)=CC(OC)=C3)=NO2)CC14CCN(C5=CC(C)=NC=C5)CC4

Description

Biochem/physiol Actions

MRK-740 is a cell penetrant, potent and selective inhibitor of PRDM9 that inhibits methylation of H3K4 in cells.

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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