• USA Home
  • SRE0013 - Interferon Alpha 2A human

EMAIL THIS PAGE TO A FRIEND
SRE0013 Sigma-Aldrich

Interferon Alpha 2A human

recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE), lyophilized powder

Synonym: INFα2A, Interferon α 2A human

Purchase

Properties

Quality Level   200
recombinant   expressed in HEK 293 cells
assay   ≥98% (SDS-PAGE)
form   lyophilized powder
storage temp.   −20°C

Description

General description

IFN-α-2a belongs to the type I interferon protein family. Interferon α 2A is one among the three variants of IFN-α2. It is produced by many cell types in response to viral infection. IFN-α-2a has antiproliferative and antitumor activities, as well as induction of apoptosis and inflammatory response.
Recombinant human IFN-α-2a is expressed in human 293 cells as a glycosylated monomer of 165 amino acids, with an average molecular weight of 20 kDa (monomer).

Application

Interferon α 2A human has been used as an inhibitor of hepatitis D virus (HDV).

Biochem/physiol Actions

Interferon α 2A might be implicated in the regression of proliferative diabetic retinopathy. Telaprevir and pegylated interferon–α-2a (PEG-IFN–α-2a) serves as a potential therapeutic method for hepatitis C virus (HCV). IFN α 2A along with IFN α 2b and IFN α2c exhibits anti-proliferative effect.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?