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SRP2053 Sigma-Aldrich

USF1 human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

Synonym: FCHL1, FCHL, HYPLIP1, MLTF, MLTFI, UEF, bHLHb11

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, Transcription Factors
biological source   human
recombinant   expressed in E. coli
assay   ≥80% (SDS-PAGE)
form   frozen liquid
mol wt   ~35.1 kDa
packaging   pkg of 10 μg
storage condition   avoid repeated freeze/thaw cycles
concentration   600 μg/mL
color   clear colorless
NCBI accession no.   NM_007122
UniProt accession no.   P22415
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... USF1(7391)

Description

Biochem/physiol Actions

Human Upstream Stimulatory Factor 1 (USF1) regulates the transcription of many genes involved in lipid and glucose homeostasis and co-localizes with familial combined hyperlipidemia (FCHL) and type 2 diabetes on chromosome 1q22-23. The USF1 protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. It is a basic helix-loop-helix leucine zipper (b-HLH-ZIP) protein that shares a common DNA-binding specificity with the c-Myc oncoproteins.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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