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SRP3260 Sigma-Aldrich

BMP-4 human

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym: BMP-2B, DVR4

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Properties

Related Categories Cell Biology, Cell Culture, General Stem Cell Biology, Growth Factors and Cytokines, Hematopoietic Stem Cell Cytokine and Growth Factors,
biological source   human
recombinant   expressed in E. coli
assay   ≥98% (HPLC)
  ≥98% (SDS-PAGE)
form   lyophilized
potency   5-10 ng/mL ED50
mol wt   mol wt 23.8 kDa
packaging   pkg of 10 μg
impurities   <0.1 EU/μg endotoxin, tested
UniProt accession no.   P12644
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... BMP4(652)

Description

Biochem/physiol Actions

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. E. coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in 5 mM HCl, pH 3.0 to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Physical form

Lyophilized with no additives.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


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Peer-Reviewed Papers
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References

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