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SRP3307 Sigma-Aldrich

FGF-8 human

Animal-component free, recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Synonym: AIGF, FGF-8b, HBGF

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Properties

Related Categories Cell Culture, FGF-4 to FGF-8, Fibroblast Growth Factors (FGF), Growth Factors and Cytokines, Reagents and Supplements More...
biological source   human
recombinant   expressed in E. coli
assay   ≥97% (HPLC)
  ≥97% (SDS-PAGE)
form   lyophilized
potency   2.0-4.0 ng/mL
mol wt   mol wt 22.5 kDa
packaging   pkg of 25 μg
impurities   endotoxin, tested
color   white to off-white
UniProt accession no.   P55075
  P55075
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... FGF8(2253)

Description

Biochem/physiol Actions

FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. . Recombinant human FGF-8 (FGF-8b) is a 22.5 kDa protein consisting of 194 amino acid residues.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Physical form

Lyophilized from 10 mM Sodium Phosphate pH, 8.0 + 75 mM NaCl.

General description

FGF-8 (FGF-8b) is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF8 A and B are identical unlike human and mouse FGF8 E and F are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. Recombinant human FGF-8 (FGF-8b) is a 22.5 kDa protein consisting of 194 amino acid residues.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Request a Serum Sample

Cell Culture Guide
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Peer-Reviewed Papers
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References

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