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SRP4038 Sigma-Aldrich

Fgf-2 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

Synonym: FGF-b, Fibroblast Growth Factor-basic, HBGF-2 Prostatropin

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Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Cytokines and Growth Factors,
biological source   mouse
recombinant   expressed in E. coli
assay   ≥95% (HPLC)
  ≥95% (SDS-PAGE)
form   lyophilized
mol wt   mol wt ~16.3 kDa
packaging   pkg of 50 μg
storage condition   avoid repeated freeze/thaw cycles
impurities   endotoxin, tested
NCBI accession no.   P15655
UniProt accession no.   P15655
shipped in   wet ice
storage temp.   −20°C
Gene Information   mouse ... Fgf2(14173)

Description

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in sterile water to 100 μg/mL.

Physical form

Sterile filtered and Lyophilized without additives.

Biochem/physiol Actions

FGF-2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. It is present in the preimplantation embryos and is important for proper development. It is also responsible for angiogenesis. FGF-2 plays a crucial role in adipogenesis and development of adipose tissues. It is associated with tumor growth and metastasis.

General description

FGF-2 (fibroblast growth factor 2) is a basic heparin binding growth factor. It is ubiquitously expressed and belongs to the FGF family. It is also referred to as BFGF (basic fibroblast growth factor). The recombinant mouse FGF-2 is a single, non-glycosylated chain containing 145 amino acids and having a molecular weight of 16.3kDa.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Request a Serum Sample

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Peer-Reviewed Papers
15

References

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