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SRP4207 Sigma-Aldrich

JE (MCP-1) from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

Synonym: CCL2, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Small inducible cytokine A2

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
biological source   mouse
recombinant   expressed in E. coli
assay   ≥98% (HPLC)
  ≥98% (SDS-PAGE)
form   lyophilized
potency   1-20 ng/mL ED50
mol wt   mol wt ~13.8 kDa
packaging   pkg of 10 μg
impurities   endotoxin, tested
NCBI accession no.   P10148
shipped in   wet ice
storage temp.   −20°C
Gene Information   mouse ... Ccl2(20296)

Description

General description

mouse JE (also known as Macrophage/Monocyte Chemotactic Protein) is a 13.8 kDa protein containing 125 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1 mg/mL. This solution can then be diluted into other aqueous buffers.

Physical form

Sterile filtered and then lyophilized with no additives.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Lipid Induced Insulin Resistance

Obesity is a well-established risk factor for the development of insulin resistance. Obesity is associated with the increased deposition of lipids in non-adipose tissue with subsequent decreases in i...
Linda Stephenson, Ph.D.
Biofiles v6 n4, 9
Keywords: Angiogenesis, Antivirals, Apoptosis, Biological processes, Cardiovascular, Catalog, Catalysis, Cell culture, Cell proliferation, Deposition, Diabetes, Events, Gene expression, Growth factors, Hormones, Inflammation, Metabolism, Metabolites, Obesity, Phosphorylations, Physiological Processes, Reductions, Transcription, Transduction, Type

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