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SRP6028 Sigma-Aldrich

Isopeptidase T (short form) human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym: Isoopeptidase T, Isopeptidase T (short form), IsopeptidaseT, USP5, Ubiquitin-specific protease 5

  •  NACRES NA.32

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Intracellular Protein Degradation, Nitric Oxide and Cell Stress, Ubiquitin and Proteases More...
biological source   human
recombinant   expressed in E. coli
assay   ≥95% (SDS-PAGE)
form   liquid
mol wt   93.4 kDa
packaging   pkg of 25 μg
concentration   ~2.0 mg/mL
impurities   Endotoxin, tested
NCBI accession no.   P45974
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... UBP5(8078)

Description

General description

Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine hydrolases that catalyze the UBPs hydrolyze isopeptide bonds between ubiquitin and the substrate protein or within polyubiquitin chains. Human isopeptidase T (isoT) is an UBP capable of binding ubiquitin that specifically disassembles free polyubiquitin chains linked through isopeptide bonds involving the K48 of ubiquitin into ubiquitin monomers.

Physical form

Supplied at a concentration of 2.0 mg/ml in 50 mM Tris, 10 mM ?-mercaptoethanol, pH 7.5.

Safety & Documentation

Safety Information

Symbol 
GHS09  GHS09
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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