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SRP6153 Sigma-Aldrich

Activin A human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

Synonym: FRP, FSH-releasing protein, Inhibin beta A

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Properties

Related Categories Cell Culture, Growth Factors and Cytokines, Reagents and Supplements, Recombinant Activin proteins, Transforming Growth Factors More...
biological source   human
recombinant   expressed in human cells
assay   ≥95% (SDS-PAGE)
form   lyophilized
mol wt   25 kDa (homodimer, non-glycosylated)
packaging   pkg of 10 μg
NCBI accession no.   P08476
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... INHBA(3624)

Description

General description

Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-? super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision’s Activin A is produced in a serum-free, chemically de?ned media.

Physical form

Lyophilized from a PBS solution.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Cell Culture Guide
Protocols & Articles

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Peer-Reviewed Papers
15

References

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