SRP6160 Sigma-Aldrich

FGF-4 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

Synonym: Fibroblast growth factor 4, HBGF4, Heparin-binding growth factor 4, K-fibroblast growth factor, KFGF

  •  NACRES NA.32



Related Categories Cell Culture, FGF-4 to FGF-8, Fibroblast Growth Factors (FGF), Growth Factors and Cytokines, Reagents and Supplements More...
biological source   human
recombinant   expressed in human cells
assay   ≥95% (SDS-PAGE)
form   lyophilized
mol wt   (17 and 27 kDa, monomer, glycosylated)
packaging   pkg of 10 μg
NCBI accession no.   P08620
UniProt accession no.   P08620
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... FGF4(2249)


General description

The FGF4 (fibroblast growth factor 4) gene is mapped to human chromosome 11q13.3. It is expressed during early embryonic development. In adults, it is strongly expressed in the testis.

Biochem/physiol Actions

FGF4 (fibroblast growth factor 4) helps in preserving the self-renewal capability of normal stem cells. The encoded protein has the ability to interact with FGFR1c (FGF receptor 1c) and FGFR2c. It also binds to FGFR3c and FGFR4, but to a lesser extent. FGFR4 is also required for cellular differentiation, morphogenesis and proliferation. It modulates proliferation and differentiation of normal stem cells, progenitor cells and cancer cells.

Physical form

Lyophilized from a PBS solution.

Preparation Note

Centrifuge the vial prior to opening.


Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


Fibroblast Growth Factors for Cell Culture

Fibroblast Growth Factors (FGFs) are potent regulators of cell proliferation, differentiation. They are critically important in normal development, tissue maintenance, wound repair and angiogenesis i...
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